EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
Content
All in Vivo Cells > Cell Card
Eye
>
Ocular Surface Ectoderm
>

Preplacodal Lens Ectoderm Cells (OSE)


Eye.OSE.PLECs
Preplacodal lens ectoderm (PPE) cells in the head ectoderm make contact with the distal portion of the optic vesicle and then specify and elongate to form the lens placode. The lens specification genes include pax6, sox2, sox3, and meis1/2, and are activated in the PPE when it makes contact with the optic vesicle.
E8.5 - E9
Presumptive Lens Ectoderm Cells
Lens
Preplacodal Lens Ectoderm Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent