The aorticopulmonary septum which is formed by cardiac neural crest cells divides the arterial blood flow into pulmonary and systemic streams. In the absence of this septum, persistent truncus arteriosus (PTA) develops, and is characterized by the formation of a single great artery at the base of the heart, that supplies systemic, coronary, and pulmonary blood flow.
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Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent