Amniotic mesenchymal stromal homogenous cells (AMMSCs) are easily isolated through mechanical and sequential trypsinization, to remove amniotic epithelial cells (AECs). The remaining mesenchymal cells are then released by digestion with collagenase. These cells have the capability to differentiate towards fates such as: adipogenic, osteogenic, chondrogenic, skeletal myogenic, cardiomyogenic, neurogenic, pancreatic, hepatic and endothelial.
It has been shown that amniotic mesenchymal stromal cells have the highest proliferation rates in vitro, when compared to fetal or adult stem cells.
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