Pancreatic Endothelial Cells (PDFE)

Pancreatic endothelial cells arise from angioblasts which migrate to the foregut endoderm and populate the emerging endodermal structures of the pancreatic buds. They eventually form the blood-vessels of the mature pancreas. Extensive mutual signaling between the endothelial cells and the pancreatic epithelium and mesenchyme participate in the regulation of pancreatic development.