Bending of the neural plate to form the neural tube occurs at two principle sites: the median hinge point (MHP), that overlies the notochord, and the dorsolateral hinge points (DLHP) that are situated at the connection of the neural plate with the remainder of the ectoderm.
In the spinal cord, DLHP cells are present only in the caudal portion, while in the rostral portion there are only MHP cells.
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