EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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All in Vivo Cells > Cell Card
Pancreas
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Dorsal Pancreatic Bud
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Acinar Progenitor Cells (DPB)


Pnc.DPB.AcPCs

Acinar progenitor cells are already committed to the acinar lineage and express acinar genes such as Mist1. These cells further mature to become mature acinar cells.


Acinar differentiation in the dorsal bud is indirectly affected by Isl1 signaling in the pancreatic mesenchyme, in a non-cell autonomous effect.
E11.5 - E12.5
Tip Cells, Exocrine Progenitors
Acinar Progenitor Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent