Dental pulp stem cells (DPSCs), are one of the five types of stem cells identified thus far in the tooth. The dental mesenchyme, which is the origin of all the five cell types, is known to derive from cranial neural crest cells.
DPSCs, which are selected by their high growth rate, differentiate in vitro into osteoblasts, adipocytes, neuronal and endothelial cells.
The other stem cell types in the tooth include the exfoliated deciduous stem cells (SHED), periodontal ligament stem cells (PDLSCs), stem cells from the apical papilla (SCAP) and dental follicle progenitor cells (DFPCs). The proliferation rate of SHEDs is significantly higher than that of DPSCs, which have a faster doubling time and a higher percentage of stem/progenitor cells in the population compared with bone marrow mesenchymal stem cells (BMSCs). SHEDs could be a desirable option as a cell source for mesenchymal stem cells (MSCs).
Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent